STEM Cell Therapy
Human amniotic membrane is derived from the placenta. Human amniotic membrane consists of collagen layers including: basement membrane and stromal matrix. Injectable, dehydrated amniotic membrane is a minimally manipulated, dehydrated, non-viable cellular amniotic membrane allograft that contains multiple extracellular matrix proteins, growth factors, cytokines and other specialty proteins present in amniotic tissue to help regenerate soft tissue. Injectable dehydrated amniotic membrane allografts are intended for the treatment of acute and chronic wounds (decubitus, arterial and venous) and modulate inflammation (Plantar Fasciitis, Achilles Tendonitis and Posterior Tibial Tendonitis).
Plantar Fasciitis is one of the most common foot problem, affecting more than 1 million persons per year. The condition may be caused by repeated trauma or overuse creating micro-tears in the Plantar Fascia. In cases recalcitrant to conservative treatments, additional diagnostic modalities such as ultrasound or magnetic resonance imaging may be used to rule out other pathologies and to confirm the diagnosis of Plantar Fasciitis.
Clinical treatment of Plantar Fasciitis vary from conservative, nonoperative tier 1 treatments, such as: oral anelgesics, rest, stretching exercises, orthotics, cryotherapy, weight loss and corticosteroid injections. More advanced tier 2 treatments such as: Night Splints, immobilization and STEM cells injection. Chronic cases of Plantar Fasciitis may advance to tier 3 treatments such as: Extracorporeal shock wave therapy, or plantar fasciotomy. Although nonoperative management leads to resolution of symptoms in approximately 90% of patients, this condition is challenging and frustrating for both patient and clinician as several months to even years of treatment is often required before symptoms abate. A treatment that reduces inflammation and heals soft–tissue damage (STEM Cell) allows for the rapid return to pain free activities of daily living.
Use of fresh human amniotic membrane in the clinical setting is precluded by a number of issues, including the risk of disease transmission. The PURION process is a method of cleaning, sterilizing, and drying human amniotic/chronionic membrane obtained from screened and tested donors. This proprietary process has allowed for the wide-spread use of an allograft material that can be stored at ambient temperature for up to 5 years. Recently, the possibility of further refining the dehydrated human amniotic/chronionic membrane with a micronization process to produce a powder has been realized. The ability to inject dehydrated human amniotic membrane (STEM Cell) allows treatment of soft tissue injuries (Plantar Fasciitis, Achilles Tendonitis and Posterior Tibial Tendonitis).
With STEM Cell Therapy, most patients are able to achieve significant pain relief, thus delaying or avoiding the need for surgery altogether. The procedure can be performed in the office setting with little or no down time at all.